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RAGE antagonist peptide is an advanced glycation end products (RAGE) antagonist. It works by preventing RAGE from binding with several of its key ligands, including HMGB-1, S100P, and S100A4. This peptide also exhibits anti-tumor and anti-inflammatory activities.
Prevents RAGE from binding with several important ligands (HMGB-1, S100P, S100A4)
Exhibits anti-tumor activities
Exhibits anti-inflammatory activities
Reduces NFκB activation in cancer cells
Inhibits glioma tumor growth
Blunts airway reactivity, airway inflammation, and goblet cell metaplasia in asthma models
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A bioactive sphingolipid potentiates LPS-induced production of inflammatory cytokines decreases the mitochondrial membrane potential and induces cell death in mouse astrocytes induces demyelination of mouse cerebellar slices at 0.1 and 1 UM inhibits PDGF-induced translocation of PKC to the cell surface and induces apoptosis in MO3.13 oligodendrocytes inhibits PPARa-mediated gene transcription in C6 glial cells at 10 and 15 UM levels are increased in postmortem brain from patients with Krabbe disease
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More